THE EPIDEMIOLOGY OF NON-ENTERIC ESCHERICHIA COLI INFECTIONS: PREVALENCE OF SEROLOGICAL GROUPS*

作者：Marvin Turck, Robert G. Petersdorf · 发表于：Journal of Clinical Investigation · 年份：1962 · DOI：10.1172/jci104635 · 被引用次数：145 · 研究领域：Escherichia coli research studies、Enterobacteriaceae and Cronobacter Research、Viral gastroenteritis research and epidemiology

Escherichia coli is an ubiquitous microorganism which is found in the gastrointestinal tract of every individual, where it usually forms a part of the normal gut flora.Extensive epidemiological, clinical, and bacteriological observations have documented the pathogenic significance of certain serological strains of E. coli in infantile diarrhea.However, although they are frequently isolated in infected sites closely related to the gastrointestinal tract, such as the appendix, gall bladder, and peritoneal cavity, little is known about the sero- logical specificity of coliform bacteria in non-en- teric infections, particularly those involving the urinary tract.Ewing (1) has emphasized that complete serological typing of E. coli should pro- vide accurate information concerning the incidence of specific strains associated with disease and per- mit evaluation of nosocomial spread.The concept that some strains of gram-negative organisms may be associated with infection more often than others is not new.Kauffman (2) ad- vanced the hypothesis that certain coliform sero- types are more prevalent in appendicitis, and he also noted that strains of certain serological groups were more frequently isolated from the urine than from feces.Others have reported that strains of certain serological groups are more commonly isolated from infected sites than from fecal specimens (3).Vahlne (4) and Sjdstedt (5) per- formed serological typing on strains of E. coli from a variety of normal and abnorma...