Childhood sexual abuse and the risk for recurrent major depression in Chinese women

作者：Enzhao Cong, Yihan Li, C. Shao, J Chen, W. Wu, Xuexue Shang, Zhaoxiang Wang, Y. Liu, Lei Liu, Chloe Gao, Yannan Li, Jinhui Wu, Hong Deng, Jing Liu, Wenhua Sang, Guanghua Liu, H. Rong, Zhaoyu Gan, Li Lei, K. Li, Jiyang Pan, Yannan Li, Yong Cui, L. Sun, L. Liu, Hongyuan Liu, Xiaolin Zhao, Y. Zhang, Rong Zhang, Yi‐Sheng Chen, X. Wang, Haiyan Li, Yi‐Sheng Chen, Yezhe Lin, Kenneth S. Kendler, Jonathan Flint, S. Shi · 发表于：Psychological Medicine · 年份：2011 · DOI：10.1017/s0033291711001462 · 被引用次数：42 · 研究领域：Child Abuse and Trauma、Child and Adolescent Psychosocial and Emotional Development、Psychopathy, Forensic Psychiatry, Sexual Offending

BACKGROUND: Studies in Western countries have repeatedly shown that women with a history of childhood sexual abuse (CSA) are at increased risk for developing major depression (MD). Would this relationship be found in China? METHOD: Three levels of CSA (non-genital, genital, and intercourse) were assessed by self-report in two groups of Han Chinese women: 1970 clinically ascertained with recurrent MD and 2597 matched controls. Diagnostic and other risk factor information was assessed at personal interview. Odds ratios (ORs) were calculated by logistic regression and regression coefficients by linear or Poisson regression. RESULTS: Any form of CSA was significantly associated with recurrent MD [OR 3.26, 95% confidence interval (CI) 1.95-5.45]. This association strengthened with increasing CSA severity: non-genital (OR 2.47, 95% CI 1.17-5.23), genital (OR 2.77, 95% CI 1.32-5.83) and intercourse (OR 13.35, 95% CI 1.83-97.42). The association between any form of CSA and MD remained significant after accounting for parental history of depression, childhood emotional neglect (CEN), childhood physical abuse (CPA) and parent-child relationship. Among the depressed women, those with CSA had an earlier age of onset, longer depressive episodes and an increased risk for generalized anxiety disorder (GAD; OR 1.92, 95% CI 1.39-2.66) and dysthymia (OR 2.16, 95% CI 1.52-3.09). CONCLUSIONS: In Chinese women CSA is strongly associated with MD and this association increases with greater severity...