Motionless phase stepping in X-ray phase contrast imaging with a compact source

作者：Houxun Miao, Lei Chen, Eric E. Bennett, Nick M. Adamo, Andrew A. Gomella, Alexa M. DeLuca, Ajay I. Patel, Nicole Y. Morgan, Han Wen · 发表于：Proceedings of the National Academy of Sciences · 年份：2013 · DOI：10.1073/pnas.1311053110 · 被引用次数：58 · 研究领域：Advanced X-ray Imaging Techniques、Crystallography and Radiation Phenomena、Laser-Plasma Interactions and Diagnostics

X-ray phase contrast imaging offers a way to visualize the internal structures of an object without the need to deposit significant radiation, and thereby alleviate the main concern in X-ray diagnostic imaging procedures today. Grating-based differential phase contrast imaging techniques are compatible with compact X-ray sources, which is a key requirement for the majority of clinical X-ray modalities. However, these methods are substantially limited by the need for mechanical phase stepping. We describe an electromagnetic phase-stepping method that eliminates mechanical motion, thus removing the constraints in speed, accuracy, and flexibility. The method is broadly applicable to both projection and tomography imaging modes. The transition from mechanical to electromagnetic scanning should greatly facilitate the translation of X-ray phase contrast techniques into mainstream applications.