Animal Cells: Noncorrelation of Length of G 1 Phase with Size after Mitosis

作者：Thomas O. Fox, Arthur B. Pardee · 发表于：Science · 年份：1970 · DOI：10.1126/science.167.3914.80 · 被引用次数：69 · 研究领域：Plant Genetic and Mutation Studies

The interval between mitosis and initiation of DNA synthesis (G(1)) varied over a fourfold range for Chinese hamster ovary cells, an established line. This was not because of size differences. Synchlronous cells of different sizes began DNA synthesis at similar times after mitosis. A novel technique of centrifugation for separating cells according to size is described.