DNA-Based Assembly of Gold Nanocrystals

作者：Colin J. Loweth, W. Brett Caldwell, Xiaogang Peng, A. Paul Alivisatos, Peter G. Schultz · 发表于：Angewandte Chemie International Edition · 年份：1999 · DOI：10.1002/(sici)1521-3773(19990614)38:12<1808::aid-anie1808>3.0.co;2-c · 被引用次数：666 · 研究领域：Advanced biosensing and bioanalysis techniques、Gold and Silver Nanoparticles Synthesis and Applications、RNA Interference and Gene Delivery

Specific, designed, nonperiodic arrangements of gold nanocrystals that are 5 and 10 nm in diameter can be prepared with double-stranded DNA serving as a template (see drawing; A' and B' denote oligonucleotide sequences complementary to sequences A and B). The methods described should be applicable to nanocrystals composed of various materials.