Type I interferon: friend or foe?

作者：Giorgio Trinchieri · 发表于：The Journal of Experimental Medicine · 年份：2010 · DOI：10.1084/jem.20101664 · 被引用次数：837 · 研究领域：interferon and immune responses、Cytokine Signaling Pathways and Interactions、Immune Response and Inflammation

Although the role of type I interferon (IFN) in the protection against viral infections has been known and studied for decades, its role in other immunologically relevant scenarios, including bacterial infections, shock, autoimmunity, and cancer, is less well defined and potentially much more complicated.