The Use of Pre-Hospital Mild Hypothermia after Resuscitation from Out-of-Hospital Cardiac Arrest

作者：Francis Kim, Michele Olsufka, Graham Nichol, Michael K. Copass, Leonard A. Cobb · 发表于：Journal of Neurotrauma · 年份：2008 · DOI：10.1089/neu.2008.0558 · 被引用次数：18 · 研究领域：Cardiac Arrest and Resuscitation、Thermal Regulation in Medicine、Non-Invasive Vital Sign Monitoring

Hypothermia has emerged as a potent neuroprotective modality following resuscitation from cardiac arrest. Although delayed hospital cooling has been demonstrated to improve outcome after cardiac arrest, in-field cooling begun immediately following the return of spontaneous circulation may be more beneficial. Cooling in the field following resuscitation, however, presents new challenges, in that the cooling method has to be portable, safe, and effective. Rapid infusion of intravenous fluid at 4 degrees C, the use of a cooling helmet, and cooling plates have all been proposed as methods for field cooling, and are all in various stages of clinical and animal testing. Whether field cooling will improve survival and neurologic outcome remains an important unanswered clinical question.