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Primary structure of the β‐subunit of Torpedo californica (Na+ + K+)‐ATPase deduced from the cDNA sequence

作者:Shunsuke Noguchi, Masaharu Noda, Hideo Takahashi, Kiyoshi Kawakami, Toshiko Ohta, Kei Nagano, Tadaaki Hirose, Seiichi Inayama, Masaru Kawamura, Shosaku Numa · 发表于:FEBS Letters · 年份:1986 · DOI:10.1016/0014-5793(86)80270-8 · 被引用次数:126 · 研究领域:ATP Synthase and ATPases Research、Ion Transport and Channel Regulation、Mass Spectrometry Techniques and Applications

DNA complementary to the Torpedo californica electroplax mRNA coding for the beta-subunit of (Na+ + K+)-ATPase has been cloned by screening a cDNA library with an oligodeoxyribonucleotide probe. Nucleotide sequence analysis of the cloned cDNA has revealed that this polypeptide consists of 305 amino acid residues (including the initiating methionine). The transmembrane topology and the potential N-glycosylation sites of this polypeptide are discussed.