MR imaging and MIBG scintigraphy of pheochromocytomas and extraadrenal functioning paragangliomas.

作者：A P van Gils, T. H. M. Falke, Arian R. van Erkel, Jan Willem Arndt, Martin P. Sandler, A G van der Mey, Roel P.L.M. Hoogma · 发表于：Radiographics · 年份：1991 · DOI：10.1148/radiographics.11.1.1671719 · 被引用次数：128 · 研究领域：Adrenal and Paraganglionic Tumors、Cancer, Hypoxia, and Metabolism、Pituitary Gland Disorders and Treatments

To compare the potential of magnetic resonance (MR) imaging and scintigraphy performed with radiotracer-labeled metaiodobenzyl-guanidine (MIBG) in localization and characterization of functioning paragangliomas, the authors analyzed results of both modalities in 33 patients. Overall sensitivity for detection was 91% for MR imaging and 80% for MIBG scintigraphy. MR imaging demonstrated 100% of adrenal paragangliomas and 75% of extraadrenal paragangliomas, whereas MIBG scintigraphy revealed 75% and 88%, respectively. MIBG scintigraphy was more specific in the characterization of paragangliomas than MR imaging (100% vs 82%). However, MR imaging demonstrated nine other lesions not seen on scintigrams. On the basis of their results and other considerations, the authors believe MR imaging is the preferred initial technique when a functioning paraganglioma is suspected.