Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors

作者：Noel A. Powell, Fred L. Ciske, Cuiman Cai, Daniel D. Holsworth, Ken Mennen, Chad A. Van Huis, Mehran Jalaie, Jacqueline E. Day, Michelle Mastronardi, Pat McConnell, Igor Mochalkin, Erli Zhang, Michael J. Ryan, John W. Bryant, Wendy T. Collard, Suzie A. Ferreira, Chungang Gu, Roxane Collins, Jeremy J. Edmunds · 发表于：Bioorganic & Medicinal Chemistry · 年份：2007 · DOI：10.1016/j.bmc.2007.05.069 · 被引用次数：52 · 研究领域：Synthesis and Biological Evaluation、Quinazolinone synthesis and applications、Receptor Mechanisms and Signaling