APC mutations occur early during colorectal tumorigenesis

作者：Steven M. Powell, N D Zilz, Yasmin Beazer-Barclay, Tracy M. Bryan, Stanley R. Hamilton, Stephen N. Thibodeau, Bert Vogelstein, Kenneth W. Kinzler · 发表于：Nature · 年份：1992 · DOI：10.1038/359235a0 · 被引用次数：1935 · 研究领域：Genetic factors in colorectal cancer、Cancer-related Molecular Pathways、Pancreatic and Hepatic Oncology Research