PREVALENCE AND RISK FACTORS FOR DIABETIC RETINOPATHY

作者：Jie Xu, Wen Bin Wei, Ming Xia Yuan, Yuan Shen, Gang Wan, Yuan Zheng, Yi Bin Li, Shuang Wang, Liang Xu, Han Fu, Liang Xiang Zhu, Xiang Lei Pu, Jian Dong Zhang, Xue Du, Yu Lin Li, Yu Ji, Xiao Gu, Yue Li, Su Pan, Xue Li Cui, Wei Bai, Yu Jie Chen, Zi Min Wang, Qing Sheng Zhu, Ying Gao, De Yuan Liu, Yun Ji, Ze Yang, Jost B. Jonas · 发表于：Retina · 年份：2011 · DOI：10.1097/iae.0b013e31821c4252 · 被引用次数：99 · 研究领域：Retinal Diseases and Treatments、Retinal Imaging and Analysis、Chronic Kidney Disease and Diabetes

In Brief Background To examine prevalence and associated factors of diabetic retinopathy in patients with Type 2 diabetes mellitus in urban communities of Beijing. Methods The community health care center–based study included subjects with diabetes mellitus and an age of 20 years to 80 years, who were recruited from 15 community health centers in urban Beijing. Diabetes mellitus was defined using the World Health Organization criteria. Fundus photographs were graded using the modified Airlie House classification system. Results Of 2,642 eligible patients, 2,007 (76.0%) subjects (1,199 women) with a mean age of 64.1 ± 9.0 years participated. The overall prevalence of diabetic retinopathy was 24.7 ± 1.0% (95% confidence interval [CI], 22.8–26.6). In binary logistic analysis, presence of diabetic retinopathy was associated with younger age (odds ratio [OR], 0.97; 95% CI, 0.95–0.98), longer duration of diabetes (OR, 1.10; 95% CI, 1.08–1.12), higher concentration of glycosylated hemoglobin HbA1c (OR, 1.23; 95% CI, 1.14–1.33), higher systolic blood pressure (OR, 1.01; 95% CI, 1.01–1.02), lower body mass index (OR, 0.95; 95% CI, 0.92–0.98), and elevated blood urea concentration (OR, 1.01; 95% CI, 1.00–1.01). Microalbuminuria was an additional associated factor (OR, 1.55; 95% CI, 1.16–2.08). Patients with microalbuminuria were 4.7 times more likely to have a severe or proliferating diabetic retinopathy than those without microalbuminuria. Conclusion In the urban population of Beijing...