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Hormonal Regulation of Food Intake

作者:Sarah A. Stanley, Katie Wynne, Barbara M. McGowan, Stephen Robert Bloom · 发表于:Physiological Reviews · 年份:2005 · DOI:10.1152/physrev.00015.2004 · 被引用次数:370 · 研究领域:Regulation of Appetite and Obesity、Adipose Tissue and Metabolism、Biochemical Analysis and Sensing Techniques

Our knowledge of the physiological systems controlling energy homeostasis has increased dramatically over the last decade. The roles of peripheral signals from adipose tissue, pancreas, and the gastrointestinal tract reflecting short- and long-term nutritional status are now being described. Such signals influence central circuits in the hypothalamus, brain stem, and limbic system to modulate neuropeptide release and hence food intake and energy expenditure. This review discusses the peripheral hormones and central neuronal pathways that contribute to control of appetite.