Risk factors for HIV-1 transmission from HIV-seropositive male blood donors to their regular female partners in northern Thailand

作者：Tippavan Nagachinta, Ann Duerr, Vinai Suriyanon, Niwes Nantachit, Sungwal Rugpao, Chanane Wanapirak, Jatupol Srisomboon, Nuonchuen Kamtorn, Sodsai Tovanabutra, Yuttana Mundee, Yupadee Yutrabutr, Rassamee Kaewvichit, Kittipong Rungruengthanakit, Melanie de Boer, Antika Tansuhaj, Lisa Flowers, Chirasak Khamboonruang, David D. Celentano, Kenrad E. Nelson · 发表于：AIDS · 年份：1997 · DOI：10.1097/00002030-199714000-00014 · 被引用次数：53 · 研究领域：HIV/AIDS Research and Interventions、Adolescent Sexual and Reproductive Health、Sex work and related issues

OBJECTIVE: To describe risks for HIV transmission from male blood donors to their regular female sex partners in Chiang Mai, Thailand. DESIGN: Cross-sectional study. METHODS: From March 1992 through September 1995, 405 HIV-seropositive male blood donors (index cases) and their regular female partners were enrolled in the study. Women with risk factors for HIV infection other than sexual contact with the index male were excluded. Couples were interviewed and examined; specimens were collected for laboratory analysis. RESULTS: Overall, 46% of the 405 women enrolled were HIV-positive. Ninety-eight per cent of male index cases had a history of sex with a female prostitute; 1.5% reported always using condoms with their regular partner. History of sexually transmitted disease (STD) and swollen inguinal lymph nodes in the female partner were associated with an increased risk of HIV infection in the female. History in the female of genital herpes [odds ratio (OR), 3.46; 95% confidence interval (CI), 1.50-8.78], gonorrhea or chlamydia infection (OR, 2.71; 95% CI, 1.39-5.53), and stable relationship of longer than 24 months (OR, 2.28; 95% CI, 1.02-5.09) were associated with an increased risk of HIV infection in the female. Consistent condom use in the past 2 years (OR, 0.10; 95% CI, 0.01-0.79) was associated with a decreased risk of HIV infection in the female. CONCLUSIONS: Married women in northern Thailand who appear otherwise to be at low risk for HIV infection may be exposed to thi...