Gamma-Aminobutyric Acid Antagonism in Visual Cortex: Different Effects on Simple, Complex, and Hypercomplex Neurons

作者：John Douglas Pettigrew, J. D. Daniels · 发表于：Science · 年份：1973 · DOI：10.1126/science.182.4107.81 · 被引用次数：55 · 研究领域：Neural dynamics and brain function、Visual perception and processing mechanisms、Neuroscience and Neuropharmacology Research

Intravenous bicuculline was used to examine how removing gamma-aminobutyric acid-mediated inhibition affects the visual response properties of single cortical neurons. Simple neurons were depressed and complex neurons showed increase in the vigor and range of responses. Hypercomplex cells were no longer inhibited by elongated stimuli. The results are consistent with present evidence concerning the origin and distribution of inhibitory connections within the cortex.