Japanese Encephalitis, Tibet, China

作者：Yixing Li, Minghua Li, Shihong Fu, Weixin Chen, Qiyong Liu, Hailin Zhang, Wa Da, Songlin Hu, Sang Dan La Mu, Ju Bai, Zundong Yin, Hong-Yue Jiang, Yuhong Guo, Dun Zhu Duo Ji, Hui-Mei Xu, Ge Li, Gu Gu Cuo Mu, Huiming Luo, Jinglin Wang, Jun Wang, Xiu-Min Ye, Zhuo Ma Yang Jin, Wei Zhang, Guijun Ning, Huanyu Wang, Guichang Li, Jian Yong, Xiaofeng Liang, Guodong Liang · 发表于：Emerging infectious diseases · 年份：2011 · DOI：10.3201/eid1705.101417 · 被引用次数：68 · 研究领域：Mosquito-borne diseases and control、Viral Infections and Vectors、Vector-borne infectious diseases

To the Editor: Tibet is located in the Qinghai-Tibet Plateau of western People’s Republic of China and has been internationally recognized as a Japanese encephalitis (JE)–nonendemic area because the average altitude is thought to be too high to facilitate the cycle of Japanese encephalitis virus (JEV) between mosquitoes and vertebrates (1,2). In addition, JE is a reportable infectious disease in China, and no clinically confirmed case has been reported in Tibet since establishment of a national case reporting system in 1951 (3,4). Neither the mosquito vector of JEV nor JEV isolates have been described in Tibet. In this study, JEV was isolated from Culex tritaeniorhynchus mosquitoes, the main vectors of JEV, collected in Tibet. Serologic assays detected anti-JEV antibodies in a large number of human and porcine serum samples collected in this region. These data demonstrate that JEV is currently circulating in Tibet. During August 5–15, 2009, mosquitoes were collected in Mainling County (altitude 2,900 m) and Medog County (altitude 1,000 m) in the Nyingchi area of Tibet. A total of 4,089 mosquitoes representing 7 species (Cx. tritaeniorhynchus, Cx. pipiens pallens, Cx. bitaeniorhynchus, Armigeres obturbans, Anopheles maculatus maculates, An. peditaeniatu, and Aedes albopictus) from 4 genera were collected in this study. The dominant mosquito species detected in Medog County was Cx. tritaeniorhynchus (2,442 [71.1%] of 3,436 mosquitoes collected there) (Table); no previous rep...