Treatment of acquired myasthenia gravis associated with thymoma in two dogs

作者：Clare Rusbridge, R. N. White, Clive M. Elwood, Simon J. Wheeler · 发表于：Journal of Small Animal Practice · 年份：1996 · DOI：10.1111/j.1748-5827.1996.tb02419.x · 被引用次数：25 · 研究领域：Myasthenia Gravis and Thymoma、Thyroid and Parathyroid Surgery、Peripheral Neuropathies and Disorders

Two cases of myasthenia gravis associated with thymoma are reported. Both were female German shepherd dogs and the thymoma was surgically resected. Aspiration pneumonia secondary to persistent megaoesophagus was a complication in both cases. The myasthenia gravis did not resolve, but there was a more satisfactory control of clinical signs with anticholinesterase treatment. Corticosteroid therapy was used in one case, but the resulting polydipsia increased the incidence of regurgitation, resulting in recurrent episodes of aspiration pneumonia.