Surface glycosylation of polymer membrane by thiol-yne click chemistry for affinity adsorption of lectin

作者：Cang Wang, Pengfei Ren, Xiao‐Jun Huang, Jian Wu, Zhi‐Kang Xu · 发表于：Chemical Communications · 年份：2011 · DOI：10.1039/c1cc10634a · 被引用次数：47 · 研究领域：Advanced biosensing and bioanalysis techniques、Click Chemistry and Applications、Glycosylation and Glycoproteins Research

We present a novel approach to constructing glycosylated surface for microporous membrane. Carbohydrate derivative can be facilely bound onto the alkyne-modified membrane surface via thiol-yne click chemistry. The glycosylated membrane surface shows an excellent affinity adsorption to lectin on the basis of carbohydrate-protein recognition.