Hepatic Resection for Metastases From Colorectal Carcinoma Is of Dubious Value

作者：William Silen · 发表于：Archives of Surgery · 年份：1989 · DOI：10.1001/archsurg.1989.01410090027004 · 被引用次数：110 · 研究领域：Hepatocellular Carcinoma Treatment and Prognosis、Pancreatic and Hepatic Oncology Research、Genetic factors in colorectal cancer

In the United States, during the past 5 to 10 years, there has been an increasingly aggressive surgical approach to resection of hepatic metastases from colorectal cancer. Operations for this purpose are currently the most common hepatic operation performed in this country, and the procedure is likely to become even more prevalent. It has been estimated that only about 1000 of the 6000 to 12 000 patients who might be potential candidates yearly actually have a resection.1While several series have reported 5-year survival rates of about 25% for those who undergo resection of hepatic metastases, comparison of this kind of outcome has been made only with retrospective series, a nonvalid control. Thus, it is not known whether surgical excision of these metastatic lesions is appropriate. A presentation and critical analysis of available data are made in this article in an attempt to provide some kind of rational approach to