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The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene

作者:Tom I. Bonner, Herman Oppermann, PETER H. SEEBURG, Stephen Kerby, M. Gunnell, Alice C. Young, Ulf Rüdiger Rapp · 发表于:Nucleic Acids Research · 年份:1986 · DOI:10.1093/nar/14.2.1009 · 被引用次数:222 · 研究领域:Receptor Mechanisms and Signaling、Pancreatic function and diabetes、RNA Interference and Gene Delivery

The complete 648 amino acid sequence of the human raf oncogene was deduced from the 2977 nucleotide sequence of a fetal liver cDNA. The cDNA has been used to obtain clones which extend the human c-raf-1 locus by an additional 18.9 kb at the 5' end and contain all the remaining coding exons.