Effects of Estrogen Therapy on Hormonal Functions and Serum Lipids in Men with Coronary Atherosclerosis

作者：Roger W. Robinson, Norio Higano, William Cohen, Ronald C. Sniffen, JOSEPH W. SHERER · 发表于：Circulation · 年份：1956 · DOI：10.1161/01.cir.14.3.365 · 被引用次数：66 · 研究领域：Hormonal and reproductive studies

Middle-aged men with coronary atherosclerosis were studied before and at intervals after initiation of estrogen therapy over a 12-month period. Serum lipid studies during treatment revealed consistent increases in phospholipid and α-lipoprotein cholesterol and decreased β-/α-lipoprotein cholesterol ratios. Concomitant endocrine studies demonstrated the expected testicular depression without apparent detriment to thyroid or adrenal function.