Codon preference and its use in identifying protein coding regions in long DNA sequences

作者：Rodger Staden, A.D. McLachian · 发表于：Nucleic Acids Research · 年份：1982 · DOI：10.1093/nar/10.1.141 · 被引用次数：466 · 研究领域：RNA and protein synthesis mechanisms、Genomics and Phylogenetic Studies、Machine Learning in Bioinformatics

This paper describes a computer method that uses codon preference to help find protein coding regions in long DNA sequences. The method can distinguish between introns and exons and can help to detect sequencing errors.