Isolation and Structure Determination of Blepharismin, a Conjugation Initiating Gamone in the Ciliate Blepharisma

作者：Takashi Kubôta, Takashi Tokoroyama, Yoshiko Tsukuda, Hirozo Koyama, Akio Miyake · 发表于：Science · 年份：1973 · DOI：10.1126/science.179.4071.400 · 被引用次数：79 · 研究领域：Marine Toxins and Detection Methods

One of the gamones (gamone II) which are effective for the induction of conjugation in Blepharisma intermedium has been isolated in a crystalline form and designated as blepharismin. From the result of chemical and spectroscopic investigations, in which x-ray crystallographic analysis was used as a definitive tool, blepharismin has been found to have the structure of calcium 3-(2'-formylamino-5'-hydroxybenzoyl)lactate.