Rhodium-Catalyzed Asymmetric Arylation

作者：Ping Tian, Hanqing Dong, Guo‐Qiang Lin · 发表于：ACS Catalysis · 年份：2011 · DOI：10.1021/cs200562n · 被引用次数：431 · 研究领域：Asymmetric Hydrogenation and Catalysis、Catalytic C–H Functionalization Methods、Asymmetric Synthesis and Catalysis

Rhodium-catalyzed asymmetric arylation (RCAA) reactions provide one of the most straightforward and powerful ways to introduce aryl fragments in an enantioselective manner. The discovery of novel chiral ligands and catalytic systems is a major focus in generating optical chiralities for RCAA reactions. In the past decade, the chelating functionalities in ligands have been significantly expanded from traditional phosphorus to interesting diene, bissulfoxide, and their hybrids. Herein we highlight the research on these distinct families of chiral ligands and describe their applications in the RCAA of arylmetals to activated alkenes, aldehydes, ketones and imines, and RCAA-tandem reactions.