Pneumomediastinum complicating bleomycin related lung damage.

作者：T Sikdar, David MacVicar, Janet E. Husband · 发表于：British Journal of Radiology · 年份：1998 · DOI：10.1259/bjr.71.851.10434917 · 被引用次数：23 · 研究领域：Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis、Pneumothorax, Barotrauma, Emphysema、Drug-Induced Adverse Reactions

We describe two patients who developed spontaneous pneumomediastinum without pneumothorax against a background of bleomycin-induced pulmonary interstitial disease whilst on treatment for metastatic germ cell tumours of the testis. Pneumomediastinum is a rare but recognized complication of bleomycin-induced lung toxicity, which has previously only been described in association with pneumothorax.