An Implantable RFID Sensor Tag toward Continuous Glucose Monitoring

作者：Zhibin Xiao, Xi Tan, Xianliang Chen, Sizheng Chen, Zijian Zhang, Hualei Zhang, Junyu Wang, Yue Huang, Peng Zhang, Li‐Rong Zheng, Hao Min · 发表于：IEEE Journal of Biomedical and Health Informatics · 年份：2015 · DOI：10.1109/jbhi.2015.2415836 · 被引用次数：132 · 研究领域：Wireless Body Area Networks、Energy Efficient Wireless Sensor Networks、Analog and Mixed-Signal Circuit Design

This paper presents a wirelessly powered implantable electrochemical sensor tag for continuous blood glucose monitoring. The system is remotely powered by a 13.56-MHz inductive link and utilizes an ISO 15693 radio frequency identification (RFID) standard for communication. This paper provides reliable and accurate measurement for changing glucose level. The sensor tag employs a long-term glucose sensor, a winding ferrite antenna, an RFID front-end, a potentiostat, a 10-bit sigma-delta analog to digital converter, an on-chip temperature sensor, and a digital baseband for protocol processing and control. A high-frequency external reader is used to power, command, and configure the sensor tag. The only off-chip support circuitry required is a tuned antenna and a glucose microsensor. The integrated chip fabricated in SMIC 0.13-μm CMOS process occupies an area of 1.2 mm ×2 mm and consumes 50 μW. The power sensitivity of the whole system is -4 dBm. The sensor tag achieves a measured glucose range of 0-30 mM with a sensitivity of 0.75 nA/mM.