BRAIN-ASSOCIATED STEM CELL ANTIGEN: AN ANTIGEN SHARED BY BRAIN AND HEMOPOIETIC STEM CELLS

作者：Edward S. Golub · 发表于：The Journal of Experimental Medicine · 年份：1972 · DOI：10.1084/jem.136.2.369 · 被引用次数：121 · 研究领域：Effects of Radiation Exposure、Cancer Cells and Metastasis、Mesenchymal stem cell research

There is an antigen on mouse brain tissue which is shared by the hemopoietic colony-forming unit or stem cell of the mouse. Treatment of bone marrow or fetal liver cells with anti-brain antisera inhibits expression of colony-forming units. The anti-stem cell antibody is not absorbed by thymus cells and thus can be distinguished from the anti-thymocyte antibody which these antisera also contain.