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HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

作者:for the DILIGEN study, Ann K. Daly, Peter T. Donaldson, Pallav Bhatnagar, Yufeng Shen, Itsik Pe’er, Aris Floratos, Mark J. Daly, David B. Goldstein, Sally John, Matthew R. Nelson, Julia Bell Graham, B. Kevin Park, John Dillon, William E. Bernal, Heather Jane Cordell, Munir Pirmohamed, Guruprasad Padur Aithal, Christopher Paul Day · 发表于:Nature Genetics · 年份:2009 · DOI:10.1038/ng.379 · 被引用次数:1056 · 研究领域:Drug-Induced Hepatotoxicity and Protection、Hepatitis C virus research、Drug Transport and Resistance Mechanisms