Advances in the Diagnosis of Altered States of Adrenocortical Function

作者：John C. Laidlaw, William J. Reddy, Dalton Jenkins, Najib Abu Haydar, Albert E. Renold, George W. Thorn · 发表于：New England Journal of Medicine · 年份：1955 · DOI：10.1056/nejm195511032531801 · 被引用次数：82 · 研究领域：Adrenal Hormones and Disorders、Hormonal Regulation and Hypertension、Stress Responses and Cortisol

GREAT advances in the diagnosis of altered states of adrenocortical function have been made possible by improvements in methods of steroid analysis and by the availability of purified preparations of ACTH and adrenocortical hormones. The development of simple methods for the measurement of blood and urinary 17-hydroxycorticoids has facilitated the estimation of the quantity of hydrocortisone secreted by the human adrenal cortex.1 , 2 The availability of ACTH has opened the way to the exploration of adrenocortical reserve in a wide variety of physiologic and pathologic states. It now appears that the intravenous administration of ACTH with the determination of 17-hydroxycorticoids and . . .