Preferential Synthesis of Ferritin and Albumin by Different Populations of Liver Polysomes

作者：Sonja J. Hicks, JamesW. Drysdale, Hamish Nisbet Munro · 发表于：Science · 年份：1969 · DOI：10.1126/science.164.3879.584 · 被引用次数：300 · 研究领域：Iron Metabolism and Disorders、Hemoglobinopathies and Related Disorders、Drug Transport and Resistance Mechanisms

Free polysomes and a mixture of free and membrane-attached polysomes were isolated separately from rat liver, and each was added to a cell-free, protein-synthesizing system. The free polysomes showed a greater capacity than the mixed polysome population for incorporation of (14)C-leucine into ferritin, whereas the reverse was true for (14)C-leucine incorporation into albumin.