Plasmid-mediated ROB-1 beta-lactamase in Pasteurella multocida from a human specimen

作者：A Rosenau, A. Labigne, F. Escande, P Courcoux, A. Philippon · 发表于：Antimicrobial Agents and Chemotherapy · 年份：1991 · DOI：10.1128/aac.35.11.2419 · 被引用次数：62 · 研究领域：Microbial infections and disease research、Plant Pathogenic Bacteria Studies、Plant Virus Research Studies

A Pasteurella multocida human isolate was resistant to beta-lactams because of production of ROB-1 beta-lactamase. The beta-lactamase was encoded by a 4.3-kb plasmid closely related to that of a Pasteurella bovine strain, as shown by Sau3A restriction profile and hybridization with a plasmid probe containing the blaROB-1 gene.