A Creutzfeldt-Jakob like syndrome due to lithium toxicity.

作者：Sarah Jane Smith, Roman S. Kocen · 发表于：Journal of Neurology Neurosurgery & Psychiatry · 年份：1988 · DOI：10.1136/jnnp.51.1.120 · 被引用次数：109 · 研究领域：Prion Diseases and Protein Misfolding、Alcoholism and Thiamine Deficiency、Lysosomal Storage Disorders Research

Two patients with lithium toxicity presented with a neurological syndrome suggesting a diagnosis of Creutzfeldt-Jakob disease. In both cases, the initial EEG was consistent with this diagnosis. Neither patient had permanent neurological sequelae and the EEG returned to normal. A careful drug history should be taken in any patient who presents with a rapidly progressive dementia even when the EEG supports a diagnosis of Creutzfeldt-Jakob disease.