BMI and Risk of Serious Upper Body Injury Following Motor Vehicle Crashes: Concordance of Real-World and Computer-Simulated Observations

作者：Shankuan Zhu, Jong‐Eun Kim, Xiaoguang Ma, Alan M. Shih, Purushottam W. Laud, Frank A. Pintar, Wei Shen, Steven B. Heymsfield, David Blair Allison · 发表于：PLoS Medicine · 年份：2010 · DOI：10.1371/journal.pmed.1000250 · 被引用次数：58 · 研究领域：Automotive and Human Injury Biomechanics、Traffic and Road Safety、Injury Epidemiology and Prevention

BACKGROUND: Men tend to have more upper body mass and fat than women, a physical characteristic that may predispose them to severe motor vehicle crash (MVC) injuries, particularly in certain body regions. This study examined MVC-related regional body injury and its association with the presence of driver obesity using both real-world data and computer crash simulation. METHODS AND FINDINGS: Real-world data were from the 2001 to 2005 National Automotive Sampling System Crashworthiness Data System. A total of 10,941 drivers who were aged 18 years or older involved in frontal collision crashes were eligible for the study. Sex-specific logistic regression models were developed to analyze the associations between MVC injury and the presence of driver obesity. In order to confirm the findings from real-world data, computer models of obese subjects were constructed and crash simulations were performed. According to real-world data, obese men had a substantially higher risk of injury, especially serious injury, to the upper body regions including head, face, thorax, and spine than normal weight men (all p<0.05). A U-shaped relation was found between body mass index (BMI) and serious injury in the abdominal region for both men and women (p<0.05 for both BMI and BMI(2)). In the high-BMI range, men were more likely to be seriously injured than were women for all body regions except the extremities and abdominal region (all p<0.05 for interaction between BMI and sex). The findings from t...