Seronegative and Seropositive Rheumatoid Arthritis

作者：JOHN H. L. BLAND, ESTELLE W. BROWN · 发表于：Annals of Internal Medicine · 年份：1964 · DOI：10.7326/0003-4819-60-1-88 · 被引用次数：39 · 研究领域：Meat and Animal Product Quality、Toxin Mechanisms and Immunotoxins、Calpain Protease Function and Regulation

Article1 January 1964Seronegative and Seropositive Rheumatoid ArthritisClinical, Radiological, and Biochemical DifferencesJOHN H. BLAND, M.D., F.A.C.P., ESTELLE W. BROWN, B.S.JOHN H. BLAND, M.D., F.A.C.P.Search for more papers by this author, ESTELLE W. BROWN, B.S.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-1-88 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe majority of patients with rheumatoid arthritis diagnosed according to the American Rheumatism Association criteria (1) have positive latex or sensitized sheep cell agglutination tests (seropositive); the remainder have negative tests (seronegative). There are certain characteristics and correlations in respect to seropositivity (2, 3). Most patients with subcutaneous nodules are in the seropositive group. Vasculitis is more common in patients with strongly positive agglutination reactions; positive reactors more frequently exhibit positive lupus erythematosus cell preparations. Splenomegaly and lymphadenopathy are more frequent in seropositive patients. Latex or sheep cell agglutination tests, positive when rheumatoid arthritis is first diagnosed, usually remain positive....References1. ROPESBENNETTCOBBJACOXJESSAR MWGASRRA: 1958 Revision of diagnostic criteria for rheumatoid arthritis. Arthritis Rheum. 2: 16, 1959. CrossrefMedlineGoogle Scholar2. VAUGHAN JH: Serum ...