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Sevenless : A Cell-Specific Homeotic Mutation of the Drosophila Eye

作者:Andrew Tomlinson, Donald F. Ready · 发表于:Science · 年份:1986 · DOI:10.1126/science.231.4736.400 · 被引用次数:196 · 研究领域:Developmental Biology and Gene Regulation、Neurobiology and Insect Physiology Research、Animal Genetics and Reproduction

Each ommatidium in the compound eye of the Drosophila mutant sevenless lacks photoreceptor number seven (R7) from the normal ommatidial complement of eight photoreceptors. A comparison of mutant and normal development reveals that this deficit is caused by the cell-specific transformation of the cell normally fated to produce R7 into a lens-secreting accessory cell, a cone cell.