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Characterization of Components of the Staphylococcus aureus mRNA Degradosome Holoenzyme-Like Complex

作者:Christelle M. Roux, Jonathon P. DeMuth, Paul M. Dunman · 发表于:Journal of Bacteriology · 年份:2011 · DOI:10.1128/jb.05485-11 · 被引用次数:114 · 研究领域:Bacterial Genetics and Biotechnology、RNA and protein synthesis mechanisms、Antimicrobial Resistance in Staphylococcus

Bacterial two-hybrid analysis identified the Staphylococcus aureus RNA degradosome-like complex to include RNase J1, RNase J2, RNase Y, polynucleotide phosphorylase (PNPase), enolase, phosphofructokinase, and a DEAD box RNA helicase. Results also revealed that the recently recognized RNase RnpA interacts with the S. aureus degradosome and that this interaction is conserved in other Gram-positive organisms.