Gel Machines Constructed from Chemically Cross-linked Actins and Myosins

作者：Akira Kakugo, Shin-ichiro Sugimoto, Jian Ping Gong, Y. Osada · 发表于：Advanced Materials · 年份：2002 · DOI：10.1002/1521-4095(20020816)14:16<1124::aid-adma1124>3.0.co;2-m · 被引用次数：107 · 研究领域：Micro and Nano Robotics、Hydrogels: synthesis, properties, applications、Advanced Materials and Mechanics

An ATP-fueled soft gel machine reconstructed from polymer-crosslinked actin muscle protein (“giant-actin”) and analogously modified myosin has been built by Osada and co-workers. The “giant-actin” gel filaments (several 1000 times larger by volume than native actin, see Figure) move along their myosin counterparts as fast as native F-actin. Such machines should work inside their body of origin without eliciting immunoreactions.