Mass spectrometric analysis of illicit drugs in wastewater and surface water

作者：Sara Castiglioni, Ettore Zuccato, Chiara Chiabrando, Roberto Fanelli, Renzo Bagnati · 发表于：Mass Spectrometry Reviews · 年份：2008 · DOI：10.1002/mas.20168 · 被引用次数：138 · 研究领域：Pharmaceutical and Antibiotic Environmental Impacts、Analytical chemistry methods development、Antibiotics Pharmacokinetics and Efficacy

Residues of illicit drugs have been recently found in urban wastewater and surface water. Their levels reflect the amount of drugs collectively excreted by consumers and can therefore be used to estimate drug abuse. An overview of the most widely used illicit drugs and of the analytical methods used for their detection in wastewater and surface water is presented here. Solid-phase extraction and high performance liquid chromatography-tandem mass spectrometry are the techniques that have been used for these investigations. Instrumental conditions and fragmentation patterns of illicit drugs and their metabolites are described.