Use of Glucagon in the Treatment of Pancreatitis

作者：Michael Knight, J. R. Condon, Rodney Smith · 发表于：BMJ · 年份：1971 · DOI：10.1136/bmj.2.5759.440 · 被引用次数：83 · 研究领域：Diet, Metabolism, and Disease、Diabetes Treatment and Management、Pancreatitis Pathology and Treatment

Four patients with pancreatic disease received glucagon intravenously. In two a definite decrease in the volume of pancreatic exocrine secretion was shown, and in one of these pancreatic juice protein and bicarbonate levels also fell. Two patients with acute pancreatitis had pronounced relief of epigastric pain associated with falls in plasma amylase after intravenous glucagon.Several mechanisms could account for the possible beneficial effect of glucagon in pancreatitis, and further studies of its use in this disease are justified.