A New Nafion-Free Bipolymeric Sensor for Selective and Sensitive Detection of Nitric Oxide

作者：Aleksander Ciszewski, Grzegorz Milczarek · 发表于：Electroanalysis · 年份：1998 · DOI：10.1002/(sici)1521-4109(199809)10:11<791::aid-elan791>3.0.co;2-h · 被引用次数：56 · 研究领域：Electrochemical sensors and biosensors、Conducting polymers and applications、Analytical Chemistry and Sensors

An amperometric/voltammetric sensor for the determination of nitric oxide based on its oxidation on a glassy carbon (GC) electrode modified by polymerized nickel(II) tetrakis(4-hydroxy-3-methoxyphenyl)porphyrin (NiTHMPP) and additionally covered by polymerized eugenol (4-allyl-2-methoxyphenol) (PE) is described. Cyclic voltammetry was used to compare the performance of Nafion and PE as selective membranes for NO sensors. Our findings showed that the electrodes with PE can be successfully applied to NO detection either by DPV (oxidation peak appeared at +0.75 V vs. Ag/AgCl) or by amperommetry at +0.8 V. The electrodes were very sensitive to NO, with detection limit of 85 nM (S/N = 3), and at the same time were also very selective against ureate (> 104:1), ascorbate (> 5 × 103:1) and nitrite (>103:1). Moreover, PE coated electrodes, comparing with those with Nafion, displayed significantly better selectivity against positively charged species: dopamine (ca. 80:1) and epinephrine (ca. 150:1).