A Naturalistic Assessment of the Motor Activity of Hyperactive Boys

作者：Linda J. Porrino · 发表于：Archives of General Psychiatry · 年份：1983 · DOI：10.1001/archpsyc.1983.04390010098013 · 被引用次数：128 · 研究领域：Attention Deficit Hyperactivity Disorder、Children's Physical and Motor Development、Sleep and Wakefulness Research

Twenty-four-hour motor activity was assessed in a naturalistic setting in 12 hyperactive boys for four weeks (672 consecutive hours). Dextroamphetamine, 15 mg/day, or placebo was administered on alternate weeks, using a double-blind ABAB design. When the boys received dextroamphetamine, motor activity was significantly decreased for about eight hours after drug administration. This decrease was followed by a period of slight but significant increases in activity ("rebound"). Dextroamphetamine decreased activity most strikingly during structured classroom activity; during physical education, however, there was a significant drug-induced increase in motor activity.