Conformational stabilization of ubiquitin yields potent and selective inhibitors of USP7

作者：Yingnan Zhang, Lijuan Zhou, Lionel Rougé, Aaron H. Phillips, Cynthia Lam, Peter Liu, Wendy Sandoval, Elizabeth Helgason, Jeremy Murray, Ingrid E. Wertz, Jacob E. Corn · 发表于：Nature Chemical Biology · 年份：2012 · DOI：10.1038/nchembio.1134 · 被引用次数：108 · 研究领域：Ubiquitin and proteasome pathways、Cancer-related Molecular Pathways、Autophagy in Disease and Therapy