Clostridium difficile-associated disease: new challenges from an established pathogen.

作者：Rebecca H. Sunenshine, L. Clifford McDonald · 发表于：Cleveland Clinic Journal of Medicine · 年份：2006 · DOI：10.3949/ccjm.73.2.187 · 被引用次数：242 · 研究领域：Clostridium difficile and Clostridium perfringens research、Nosocomial Infections in ICU、Microscopic Colitis

Clostridium difficile-associated disease (CDAD) can range from uncomplicated diarrhea to sepsis and even death. CDAD rates and severity are increasing, possibly due to a new strain. Transmission of C difficile occurs primarily in health care facilities via the fecal-oral route following transient contamination of the hands of health care workers and patients; contamination of the patient care environment also plays an important role.