Histological evidence of carcinoma in a hepatic tumour associated with oral contraceptives.

作者：Michael R. Davis, Bernard C Portmann, MARTIN SEARLE, R. DOUGLAS WRIGHT, Reese K. Williams · 发表于：BMJ · 年份：1975 · DOI：10.1136/bmj.4.5995.496 · 被引用次数：142 · 研究领域：Cholangiocarcinoma and Gallbladder Cancer Studies、Hepatocellular Carcinoma Treatment and Prognosis

A primary hepatic tumour occurred in a 21-year-old woman who had been taking oral contraceptives for two years; she was treated by partial hepatectomy. Part of the neoplasm showed features suggestive of focal nodular hyperplasia, while the remainder had the histological characteristics of a well-differentiated hepatocellular carcinoma. This is the first report of malignant transformation of a tumour in a patient taking oral contraceptives.