Markers of Oxidative Stress during Diabetes Mellitus

作者：Brahm Kumar Tiwari, Kanti Bhooshan Pandey, A. B. Abidi, Syed Ibrahim Rizvi · 发表于：Journal of Biomarkers · 年份：2013 · DOI：10.1155/2013/378790 · 被引用次数：523 · 研究领域：Advanced Glycation End Products research、Adipose Tissue and Metabolism、Biochemical effects in animals

The prevalence of diabetes mellitus is rising all over the world. Uncontrolled state of hyperglycemia due to defects in insulin secretion/action leads to a variety of complications including peripheral vascular diseases, nephropathy, neuropathy, retinopathy, morbidity, and/or mortality. Large body of evidence suggests major role of reactive oxygen species/oxidative stress in development and progression of diabetic complications. In the present paper, we have discussed the recent researches on the biomarkers of oxidative stress during type 2 diabetes mellitus.