Fluid-attenuated Inversion Recovery Ring Sign as a Marker of Dysembryoplastic Neuroepithelial Tumors

作者：Hemant Parmar, Cynthia Hawkins, Rodrigo V. Ozelame, Sylvester H. Chuang, James T. Rutka, Susan Blaser · 发表于：Journal of Computer Assisted Tomography · 年份：2007 · DOI：10.1097/01.rct.0000243453.33610.9d · 被引用次数：75 · 研究领域：Epilepsy research and treatment、Cerebrospinal fluid and hydrocephalus、Glioma Diagnosis and Treatment

PURPOSE: The aim of our study is to describe the hyperintense ring sign on fluid-attenuated inversion recovery (FLAIR) images in patients with dysembryoplastic neuroepithelial tumors (DNET), to discuss the radiopathologic correlation for this appearance, and to determine its role in preoperative diagnosis of DNETs. MATERIALS AND METHODS: We retrospectively analyzed imaging features in 11 patients with pathological diagnosis of DNET. All patients had undergone surgery for refractory seizures. All had FLAIR imaging sequences performed on a 1.5-T magnetic resonance scanner. Clinical and pathological details in all cases were examined. Twenty-one age matched patients with pathologically confirmed low-grade glioma (n = 11), oligodendroglioma (n = 2), and ganglioglioma (n = 8) in similar locations acted as control cases. Ten patients had follow-up imaging. RESULTS: There were 11 patients with DNET (5 girls and 6 boys). The age of presentation varied from 4 to 18 years (average, 9 years 1 month). Tumors were located in the temporal (n = 5), frontal (n = 4), parietal (n = 1), and occipital (n = 1) lobes. In 9 patients (82% sensitivity), the FLAIR images showed a well-defined hyperintense ring around these tumors, either as a complete or incomplete ring. Among the 21 control cases, the hyperintense ring sign was seen in 2 cases (90% specificity): one with low-grade glioma and one with ganglioglioma. Pathological evaluation of the DNETs suggested the hyperintense ring might correspond ...