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A SYSTEM FOR THE CLINICAL STAGING OF LUNG CANCER

作者:Clifton F. Mountain, David Carr, Winston A. Anderson · 发表于:American Journal of Roentgenology · 年份:1974 · DOI:10.2214/ajr.120.1.130 · 被引用次数:327 · 研究领域:Lung Cancer Diagnosis and Treatment、Lung Cancer Treatments and Mutations、Radiomics and Machine Learning in Medical Imaging

S TAGING of neoplastic disease is the procedure of assigning a simple coded designator to a patient in accordance with an established set of rules. Its purpose is to classify patients and group them with respect to the anatomic extent or biologic severity of their disease. Clinical staging is based only on those measures of disease extent which are available from diagnostic or evaluative studies undertaken prior to instituting therapy. This classification of patients into relatively homogeneous groups, with respect to estimates of their prognosis, is essential if different modalities of treatment are to be compared and if results are to be communicated in meaningful terms. The central problems in designing a meaningful staging system are: (I) to identify and give proportionate weight to those factors which will reliably and validly predict survival; and (2) to develop rules which, when applied to these factors, will permit assignment of an index of disease extent. The essential character of such an index is that patients within any stagegroup who survive equivalent treatment will demonstrate a generally similar ageadjusted life expectancy. A major constraint on any system of classifying the extent of disease is that it must be easily understood and remembered; therefore, it must be based on relatively few predicting factors. Only a relatively uncomplicated system will lend itself to widespread utilization. Among the systems of classification proposed by international organiza...