Idiopathic Pulmonary Fibrosis: Aberrant Recapitulation of Developmental Programs?

作者：Moisés Selman, Annie Pardo, Naftali Kaminski · 发表于：PLoS Medicine · 年份：2008 · DOI：10.1371/journal.pmed.0050062 · 被引用次数：344 · 研究领域：Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis、Neonatal Respiratory Health Research、Wnt/β-catenin signaling in development and cancer

The authors discuss evidence suggesting that embryonic signaling pathways involved in epithelium/mesenchymal communication and epithelial cell plasticity may be aberrantly switched on in idiopathic pulmonary fibrosis.