Solvent-free N-arylation of amines with arylboronic acids under ball milling conditions

作者：Xingyi Zhu, Qihong Zhang, Weike Su · 发表于：RSC Advances · 年份：2014 · DOI：10.1039/c4ra02952f · 被引用次数：33 · 研究领域：Catalytic Cross-Coupling Reactions、Innovative Microfluidic and Catalytic Techniques Innovation、Chemical Synthesis and Analysis

Solvent-free coupling reactions of arylboronic acids with various amines were presented under ball milling conditions, achieving the aromatic amine coupling products with yields ranging from moderate to good. This type of mechano-chemistry exhibited advantages of solvent-free property, high efficiency, simple work-up procedure and eco-friendliness.