Cluster of genes in Escherichia coli for ribosomal proteins, ribosomal RNA, and RNA polymerase subunits.
作者:Lasse Lindahl, S. Richard Jaskunas, Patrick P. Dennis, Michio Nomura · 发表于:Proceedings of the National Academy of Sciences · 年份:1975 · DOI:10.1073/pnas.72.7.2743 · 被引用次数:94 · 研究领域:RNA modifications and cancer、DNA Repair Mechanisms、RNA and protein synthesis mechanisms
The transducing phage lambdarifd18 isolated by Kirschbaum and Konrad [(1973 J. Bacteriol. 116, 517-526] was found to carry structural genes for several 50S ribosomal proteins and 16S and 23S rRNA. It has previously been demonstrated [Kirschbaum & Scaife (1974) Mol. Gen. Genet. 132, 193-201] that this phage carries genes for the DNA-dependent RNA polymerase (nucleosidetriphosphate:RNA nucleotidyltransferase; EC 2.7.7.6) subunits beta and beta'. Thus, the region of the E. coli chromosome carried by lambdarifd18 contains a cluster of genes essential for transcription and translation.